General Western Blot Reagents
Abcam WY 14643, PPARalpha agonist, 10MG
MW 323.8 g/mol, Purity >99%. Selective PPARα agonist (EC₅₀ values are 0.63, 32 and >100 μM at PPARα, PPARγ and PPARδ receptors respectively). Able to reduce inflammatory responses in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Bisindolylmaleimide x I hydrochloride, PKC inhibitor, 1MG
MW 489 Da, Purity >98%. Selective, cell-permeable protein kinase C (PKC) inhibitor that displays 10-fold greater selectivity for PKCα (IC₅₀ = 9 nM) and 4-fold greater selectivity for PKCβI (IC₅₀ = 28 nM) over Ca²+-independent PKCε (IC₅₀ = 108 nM). Enhances cardiac contractility and protection from heart failure. Prevents T-cell activation and proliferation (IC₅₀s ranging from 30-150 nM) associated with chronic inflammatory responses in vivo. Also inhibits GRK2, GRK5, and GRK6 (IC₅₀ values are 29, 3.6, and 16 μM, respectively).
The product is subject to the following: Abcam Restricted Use Statement
Abcam Oligomycin A, ATP synthase inhibitor, 5MG
MW 791.1 Da, Purity >97%. Macrolide antibiotic. ATP synthase inhibitor. Blocks the proton channel (Fo subunit) to uncouple oxidative phosphorylation. Shows antitumor activity. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Fluconazole, Cytochrome P450 inhibitor, 50MG
MW 306.27 Da, Purity >99%. Triazole antifungal agent. Cytochrome P450 inhibitor (IC₅₀ values are 30.3, 12.3, 13.1 μM for CYP2C9, CYP2C19 and CYP3A4, respectively). Penetrates the blood-brain barrier.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Deltamethrin, protein phosphatase 2B inhibitor, 50MG
MW 505.2 Da, Purity >98%. Potent protein phosphatase 2B inhibitor (IC₅₀ = 0.03 nM). Induces neurotoxicity by slowing the opening and closing of Na+ channels. Active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam alpha-Calcitonin Gene Related Peptide (human), CGRP agonist, 500UG
MW 3789.3 Da, Purity >95%. alpha-Calcitonin Gene Related Peptide (human), CGRP agonist. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Abcam GR113808, selective 5-HT4 antagonist, 10MG
MW 393.5 g/mol, Purity >99%. Potent, highly selective 5-HT₄ receptor antagonist (pKb = 8.8). Displays > 300-fold selectivity over 5-HT₁A, 5-HT₁B, 5-HT₂A, 5-HT₂C and 5-HT₃ receptors. Decreases water intake and potentiates drinking.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Vimentin peptide, 1MG
Vimentin peptide is a Synthetic blocking peptide. >90% purity and suitable for BL.
Protein/ Peptide/ Enzyme Synonyms: Vimentin, VIM
Conjugation: Unconjugated
The product is subject to the following: Abcam Restricted Use Statement
Abcam 2'-Deo x ythymidine 5'-monophosphate disodium salt, Deo x yribonucleotide., 1G
MW 366.2 g/mol, Purity >98%. Deoxyribonucleotide used as a substrate in many molecular biology applications.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Asta x anthin, Antio x idant agent, 25MG
MW 596.8 Da, Purity >97%. Potent antioxidant agent. PPARα agonist and PPARγ antagonist. Free radical scavenger. Reduces oxidative stress. Induces apoptosis. Inhibits NF-κB. Shows anti-inflammatory, antihypertensive, cardioprotective, neuroprotective and antitumor effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Abcam SMI-4a, ATP-competitive Pim kinase inhibitor, 25MG
MW 273.23 Da. Potent, selective, cell-permeable, ATP-competitive Pim-1 kinase inhibitor (IC₅₀ = 17 nM). Moderately potent against Pim-2 kinase. Selective versus a panel of other serine/threonine and tyrosine kinases. Inhibits the growth of myeloid and lymphoid cell lines. Induces cell cycle arrest in leukemia and prostate cancer cells.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Clindamycin, inhibits protein synthesis, 10MG
MW 425 Da, Purity >99%. Broad spectrum antimicrobial agent. Active against Gram-positive and Gram-negative bacteria and selected protozoa. Competitive inhibitor of peptide formation in large 50S ribosomal unit. Orally active in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Crystal violet, Cation-based violet dye, 25G
MW 408 Da. Cation-based violet dye. Interacts with aqueous KI - I₂ during Gram staining to produce a precipitate. Histological stain for Gram-positive bacteria and DNA. Shows antibacterial, antifungal, and anthelmintic effects in vivo. .
The product is subject to the following: Abcam Restricted Use Statement
Abcam Pa x illine, Ca2+-activated K+channel blocker, 5MG
MW 435.6 Da, Purity >98%. Potent high-conductance Ca2+-activated K+channel blocker (Ki = 2 nM, α-subunit BKCa)Inhibits sarco/endoplasmic reticulum Ca2+-ATPase (IC50 = 5 - 50 μM). Shows anticonvulsant effects *in vivo.*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam AM 80, retinoic acid receptor alpha/beta (RAR alpha/beta) agonist, 50MG
MW 351.44 g/mol, Purity >98%. Selective retinoic acid receptor α/β (RARα/β) agonist. Induces differentiation and anti-cancer activity in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement